YN360226 Broflanilide 1207727-04-5

Broflanilide is a potential insecticide and metabolized to Desmethyl-Broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL)GABA Receptor, and inhibitsS. lituraRDL GABAR, with an IC50 v...

YN330310 BD-AcAc 2 1208313-97-6

BD-AcAc 2, added in diet, could elevated mean blood ketone bodies of 3.5 mm and lowered plasma glucose, insulin, and leptin in animals; ketone ester given orally would delay CNS-OT seizures in rats breathing hyperbaric oxygen.

YN372273 JZL195 1210004-12-8

JZL195 is a potent inhibitor of both FAAH and MAGL with IC50s of 2 and 4 nM respectively.

YN480434 (Rac)-LM11A-31 dihydrochlo... 1214672-15-7

(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a non-peptide p75NTR(neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) anta...

YN321004 CP-809101 hydrochloride 1215721-40-6

CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist with pEC50 of 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors respectively.

YN360024 DMCM hydrochloride 1215833-62-7

DMCM hydrochloride is a nonselective full inverse agonist ofbenzodiazepine. DMCM shows bnding afinity at human recombinantGABAA αxβ3γ2 receptorsubtypes with Kis of 10nM, 13nM, 7.5nM, 2.2nM for α1, α2, α3, and α5  ...

YN320268 YM-298198 hydrochloride 1216398-09-2

YM-298198 hydrochloride is a high-affinity, selective, and noncompetitive antagonist ofmetabotropic glutamate receptor type 1 (mGluR1). YM-298198 hydrochloride can be used for the research of neurological disorders.

YN320422 Trap-101 hydrochloride 1216621-00-9

Trap-101 hydrochloride is a potent, selective and competitive antagonist ofNOP receptorsover classical opioid receptors. Trap-101 stimulates GTPγ35S binding to CHOhNOPmembranes with pKi values. of 8.65, 6.60, 6.14 and <...

YN321458 Mirtazapine D3 1216678-68-0

Mirtazapine D3 (Org3770 D3; 6-Azamianserin D3) is a deuterium labeled Mirtazapine. Mirtazapine is a5-HT receptorinhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaS...

YN380105 Rasagiline 13C3 mesylate rac... 1216757-55-9

Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible inhibitor of monoamine oxidase.

YN480900 Bupropion morpholinol D6 1216893-18-3

Bupropion morpholinol D6 is a useful labeled metabolite of Bupropion.

YN360682 GYKI-47261 dihydrochloride 1217049-32-5

GYKI-47261 dihydrochloride is a competitive, orally active, and selectiveAMPA receptorantagonist with an IC50 of 2.5μM. GYKI-47261 has broad spectrum anticonvulsive activity and neuroprotective effects. GYKI-47261 di...

YN321375 Quetiapine D4 hemifumarate 1217310-65-0

Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate. Quetiapine hemifumarate is a 5-HT receptors agonist and a dopamine receptor antagonist. Antidepressant and anxiolytic effects.

YN320804 LY 344864 hydrochloride 1217756-94-9

LY 344864 hydrochloride is a selective5-HT1Fagonist with a Ki of 6nM.

YN320063 4-Hydroxypropranolol D7 hydr... 1219804-03-1

4-Hydroxypropranolol D7 hydrochloride ((±)-4-hydroxy Propranolol D7 hydrochloride) is a deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol, with potency com...

YN360970 (±)-Anatoxin A fumarate 1219922-30-1

(±)-Anatoxin A fumarate is a natural alkaloid isolated from freshwatercyanobacterium.(±)-Anatoxin A fumarate is a potentnicotinic receptoragonist and exhibitsKivalues of 1.25nM and 1.84μM for binding to putative α4β2-type nA...

YN360248 TC-I 2014 1221349-53-6

TC-I 2014 (compound 5) is a potent and orally active Benzimidazole-containingtransient receptor potential melastatin 8 (TRPM8)antagonist, with IC50 values of 0.8nM, 3.0nM and 4.4nM for canine, human and rat channels respe...

YN360334 A-1165442 1221443-94-2

A-1165442 is a potent, competitive and orally availableTRPV1antagonist with an IC50 of 9nM for human TRPV1.

YN320571 MK-3697 1224846-01-8

MK-3697 is an isonicotinamide small molecule, acting as a potent and selective Orexin 2 receptor antagonist with Ki = 0.95nM.

YN1730026 SB-277011 dihydrochloride 1226917-67-4

SB-277011 dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetratedopamine D3receptorantagonist, withpKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1Drecep...