YN270542 Conophylline 142741-24-0

Conophylline is a vinca alkaloid extracted from leaves of a tropical plantErvatamia microphylla. Conophylline is a differentiation inducer of for pancreatic cells. Conophylline suppresses HSC and induces apoptosis.

YN483370 Timosaponin B III 142759-74-8

Timosaponin B III is a major bioactive steroidal saponin isolated fromAnemarrhena asphodeloidesBge, and exhibits anti-inflammatory, anti-platelet aggregative and anti-depressive effects .

YN372830 (S)-(+)-O-Desmethyl Venlaf... 142761-12-4

(S)-(+)-O-Desmethyl Venlafaxine is a S-enantiomer of O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reupta...

YN380271 Silybin B 142797-34-0

Silybin B, a flavonolignan separated fromSilybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease...

YN321983 Galanin Receptor Ligand M3... 142846-71-7

Galanin Receptor Lig and M35 is a high-affinity lig and and antagonist ofgalanin receptor(Kd=0.1nM). Galanin Receptor Lig and M35 exerts aKivalues of 0.11 and 2.0nM for human galanin receptor type 1 and 2, respectively.

YN484260 Lipid peroxidation inhibitor ... 142873-41-4

Lipid peroxidation inhibitor 1 is alipid peroxidationinhibitor with an IC50 of 0.07μM.

YN321422 Naratriptan hydrochloride 143388-64-1

Naratriptan HCl is a triptan agent that is used for the treatment of migraine headaches.

YN483752 (Arg)9 143413-47-2

(Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide; exhibits neuroprotective activity with an IC50 of 0.78μM in the glutamic acid model.

YN481579 Rocuronium 143558-00-3

Rocuronium (Org-9426) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia.

YN360126 GYKI 53655 hydrochloride 143692-48-2

GYKI 53655 (LY300168) hydrochloride is an α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) antagonist.

YN483769 PACAP (6-38), human, ovin... 143748-18-9

PACAP (6-38), human, ovine, rat is a potentPACAP receptorantagonist with IC50s of 30, 600, and 40nM forPACAP type I receptor,PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectivel...

YN320238 SB-200646A 143797-62-0

SB-200646A is the first selective5-HT2B/2Cover 5-HT2Areceptor antagonist with pKi values. of 7.5, 6.9 and 5.2 for5-HT2B,5-HT2C and 5-HT2A, respectively. SB-200646A is orally active and has electrophysiological a...

YN320239 SB-200646 143797-63-1

SB 200646 (SB 200646A) is a potent, selective and oral-active antagonist of 5-HT2B/2C over 5-HT2A receptor with 50 fold selectivity. The pKi for rat 5-HT2C receptor, rat 5-HT2B receptor and rat 5-HT2A receptor ...

YN361068 Ro 41-3290 143943-72-0

Ro 41-3290 is the desethylated derivative of Ro 41-3696, which is a nonbenzodiazepine partial agonist at thebenzodiazepine receptor. Ro 41-3290 is an investigational hypnotic.

YN483979 PACAP-38 (16-38), human, ... 144025-82-1

PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP is a potent activator of cAMP formation.

YN483784 Xenin 144092-28-4

Xenin is a 25-amino acid peptide initially isolated from human gastric mucosa. Xenin is a gut hormone that can reduce food intake.

YN380294 β-Amyloid (22-35) 144189-71-9

β-Amyloid 22-35 (Amyloid β-Protein 22-35), the residues 22-35 fragment ofβ-amyloid protein, has a cytotoxic effect on cultured neurons from the rat hippocampus in serum-free medium. β-Amyloid 22-35 forms aggregates and typical amy...

YN321971 Valorphin 144313-54-2

Valorphin is an endogenous hemoglobin β-chain (33-39) fragment with opioid analgesic activity, binds to ratmu-opioid receptor, with an IC50 of 14nM; Valorphin also shows anti-tumor activity.

YN483873 Amyloid β-peptide (1-40) rat 144409-98-3

Amyloid β-peptide (1-40) (rat) is the prone-to-aggregation product of amyloid precursor protein proteolytic cleavage, and is the major constituent of senile plaques observed in the brain of Alzheimer’s disease.

YN321329 Paliperidone 144598-75-4

Paliperidone, the main active metabolite of Risperidone, is a potent serotonin-2A and dopamine-2 receptor antagonist, used in the treatment of schizophrenia.