PLX7904
Cat. No. :YN350195
CAS No. :1393465-84-3
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order@ubiochem.com| Product Name: | PLX7904 |
| CAS NO.: | 1393465-84-3 |
| Chemical Name: | |
| Synonyms: | PB04 |
| Molecular Weight: | 512.53 |
| Molecular Formula: | C₂₄H₂₂F₂N₆O₃S |
| SMILES: | O=S(NC1=CC=C(F)C(C(C2=CNC3=NC=C(C4=CN=C(C5CC5)N=C4)C=C32)=O)=C1F)(N(CC)C)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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