Regorafenib Hydrochloride
Cat. No. :YN350134
CAS No. :835621-07-3
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order@ubiochem.com| Product Name: | Regorafenib Hydrochloride |
| CAS NO.: | 835621-07-3 |
| Chemical Name: | |
| Synonyms: | Stivarga, BAY 73-4506 hydrochloride |
| Molecular Weight: | 519.28 |
| Molecular Formula: | C₂₁H₁₆Cl₂F₄N₄O₃ |
| SMILES: | ClC1=C(C(F)(F)F)C=C(NC(NC2=C(F)C=C(OC3=CC=NC(C(NC)=O)=C3)C=C2)=O)C=C1.Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Regorafenib (Stivarga, BAY 73-4506) Hydrochloride is a multi-target inhibitor for VEGFR1, Murine VEGFR2/3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM, 4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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