Regorafenib monohydrate
Cat. No. :YN350030
CAS No. :1019206-88-2
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Product Name: | Regorafenib monohydrate |
CAS NO.: | 1019206-88-2 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 500.83 |
Molecular Formula: | C₂₁H₁₇ClF₄N₄O₄ |
SMILES: | O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F.O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Regorafenib is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respectively. |
IC50&Target: | |
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