B-Raf inhibitor 1 dihydrochloride
Cat. No. :YN350141
CAS No. :1191385-19-9
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order@ubiochem.com| Product Name: | B-Raf inhibitor 1 dihydrochloride |
| CAS NO.: | 1191385-19-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 551.86 |
| Molecular Formula: | C₂₆H₂₁Cl₃N₈ |
| SMILES: | CC1=CC=C2C(C=CN=C2NC3=CC=C(Cl)C=C3)=C1NC4=NC=CC=C4C5=NC=NC6=C5N=CN6.[H]Cl.[H]Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | B-Raf inhibitor 1 (Compound 13) is a type IIA Raf inhibitor which bind to the DFG-out conformation with ki of 1 nM,1 nM,and 0.3 nM for B-Raf(WT), B-Raf(V600E) and C-Raf, respectively. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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