Belvarafenib
Cat. No. :YN350061
CAS No. :1446113-23-0
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5mg
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Product Name: | Belvarafenib |
CAS NO.: | 1446113-23-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 478.93 |
Molecular Formula: | C₂₃H₁₆ClFN₆OS |
SMILES: | O=C(C(C1=NC=N2)=CSC1=C2N)NC(C3=C4C(NC(C=CC=C5Cl)=C5F)=NC=C3)=C(C=C4)C |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Belvarafenib (GDC5573, HM95573, RG6185) is a selective and orally bioavailable pan-RAF kinase inhibitor with IC50 values of 41 nM, 7 nM and 2 nM for BRAF WT, BRAF(V600E) and CRAF kinases, respectively. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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