ML786 dihydrochloride
Cat. No. :YN350153
CAS No. :1237536-18-3
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order@ubiochem.com| Product Name: | ML786 dihydrochloride |
| CAS NO.: | 1237536-18-3 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 611.48 |
| Molecular Formula: | C₂₉H₃₁Cl₂F₃N₄O₃ |
| SMILES: | O=C(CC1)NC2=C1C(OC3=CC=C(CC[C@@H](NC(C4=CC(C(F)(F)F)=CC(C(C)(C)N)=C4)=O)C5)C5=C3)=CC=N2.Cl.Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | ML786 dihydrochloride potent and orally bioavailable Rafinhibitor, with IC50s of 2.1, 4.2, and 2.5nM forV600EΔB-Raf,wt B-Raf, and C-Raf, respectively. ML786 dihydrochloride also inhibitsAbl-1,DDR2,EPHA2,KDR, and RET(IC50=<0.5, 7.0, 11, 6.2, 0.8nM). ML786 dihydrochloride can be used for the research of cancers. |
| IC50&Target: | |
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| Clinical Trial: | |
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| References: |
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