Regorafenib
Cat. No. :YN350029
CAS No. :755037-03-7
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Product Name: | Regorafenib |
CAS NO.: | 755037-03-7 |
Chemical Name: | |
Synonyms: | Fluoro-Sorafenib |
Molecular Weight: | 482.82 |
Molecular Formula: | C₂₁H₁₅ClF₄N₄O₃ |
SMILES: | O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. |
IC50&Target: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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