AZ304
Cat. No. :YN350088
CAS No. :942507-42-8
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order@ubiochem.com| Product Name: | AZ304 |
| CAS NO.: | 942507-42-8 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 451.52 |
| Molecular Formula: | C₂₇H₂₅N₅O₂ |
| SMILES: | O=C(NC1=CC=C(C)C(NC2=C3C=CC(OC)=CC3=NC=N2)=C1)C4=CC=CC(C(C)(C#N)C)=C4 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | AZ304 is an ATP-competitive dualBRAFkinase inhibitor, potently inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC50s of 79nM, 38nM and 68nM, respectively. AZ304 also has significant effect on other kinases, such as p38 (IC50, 6nM), CSF1R (IC50, 35nM). Anti-tumor activity. |
| IC50&Target: | |
| In Vitro: | |
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| Solvent & Solubility: | |
| References: |
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