Cabozantinib
Cat. No. :YN440239
CAS No. :849217-68-1
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order@ubiochem.com| Product Name: | Cabozantinib |
| CAS NO.: | 849217-68-1 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 501.51 |
| Molecular Formula: | C₂₈H₂₄FN₃O₅ |
| SMILES: | O=C(C1(CC1)C(NC2=CC=C(F)C=C2)=O)NC3=CC=C(C=C3)OC4=C5C=C(OC)C(OC)=CC5=NC=C4 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. |
| IC50&Target: | |
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| Solvent & Solubility: | |
| References: |
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