AZD3229
Cat. No. :YN440160
CAS No. :2248003-60-1
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order@ubiochem.com| Product Name: | AZD3229 |
| CAS NO.: | 2248003-60-1 |
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| Molecular Weight: | 479.51 |
| Molecular Formula: | C₂₄H₂₆FN₇O₃ |
| SMILES: | COCCOC1=CC(F)=C2C(N=CN=C2NC3=CC=C(NC(CN4C=C(C(C)C)N=N4)=O)C=C3)=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | AZD3229 is a potent, pan-KIT mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM), with good margin to KDR-driven effects. It also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V). |
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