Motesanib Diphosphate
Cat. No. :YN440066
CAS No. :857876-30-3
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order@ubiochem.com| Product Name: | Motesanib Diphosphate |
| CAS NO.: | 857876-30-3 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 569.44 |
| Molecular Formula: | C₂₂H₂₉N₅O₉P₂ |
| SMILES: | O=C(C1=CC=CN=C1NCC2=CC=NC=C2)NC3=CC(NCC4(C)C)=C4C=C3.O=P(O)(O)O.O=P(O)(O)O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret. Phase 3. |
| IC50&Target: | |
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| In Vivo: | |
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