Masitinib mesylate
Cat. No. :YN440064
CAS No. :1048007-93-7
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order@ubiochem.com| Product Name: | Masitinib mesylate |
| CAS NO.: | 1048007-93-7 |
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| Molecular Weight: | 594.75 |
| Molecular Formula: | C₂₉H₃₄N₆O₄S₂ |
| SMILES: | O=C(NC1=CC=C(C(NC2=NC(C3=CC=CN=C3)=CS2)=C1)C)C4=CC=C(CN5CCN(CC5)C)C=C4.CS(=O)(O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor ofc-Kit(IC50=200nM for human recombinant c-Kit). It also inhibits PDGFRα/β(IC50s=540/800nM),Lyn(IC50= 510nM for LynB),Lck, and , to a lesser extent,FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity . |
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