Tandutinib
Cat. No. :YN440056
CAS No. :387867-13-2
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5mg
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Product Name: | Tandutinib |
CAS NO.: | 387867-13-2 |
Chemical Name: | |
Synonyms: | CT 53518, NSC726292, MLN518 |
Molecular Weight: | 562.70 |
Molecular Formula: | C₃₁H₄₂N₆O₄ |
SMILES: | O=C(N1CCN(C2=C(C(C=C3OCCCN4CCCCC4)=NC=N2)C=C3OC)CC1)NC5=CC=C(OC(C)C)C=C5 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Tandutinib (MLN518, CT53518) is a potent FLT3 antagonist with IC50 of 0.22 μM, also inhibits PDGFR and c-Kit, 15 to 20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 2. |
IC50&Target: | |
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References: |
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