Dovitinib
Cat. No. :YN440410
CAS No. :405169-16-6
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order@ubiochem.com| Product Name: | Dovitinib |
| CAS NO.: | 405169-16-6 |
| Chemical Name: | |
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| Molecular Weight: | 392.43 |
| Molecular Formula: | C₂₁H₂₁FN₆O |
| SMILES: | O=C1NC(C=CC=C2F)=C2C(N)=C1C3=NC4=CC=C(N5CCN(C)CC5)C=C4N3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays. Phase 4. |
| IC50&Target: | |
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