Toceranib
Cat. No. :YN440077
CAS No. :356068-94-5
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5mg
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Product Name: | Toceranib |
CAS NO.: | 356068-94-5 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 396.46 |
Molecular Formula: | C₂₂H₂₅FN₄O₂ |
SMILES: | O=C(NCCN1CCCC1)C2=C(NC(/C=C3C(NC4=C3C=C(C=C4)F)=O)=C2C)C |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR,VEGFR, and Kitwith Kis of 5 and 6nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors. |
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