Ripretinib
Cat. No. :YN440156
CAS No. :1442472-39-0
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order@ubiochem.com| Product Name: | Ripretinib |
| CAS NO.: | 1442472-39-0 |
| Chemical Name: | |
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| Molecular Weight: | 510.36 |
| Molecular Formula: | C₂₄H₂₁BrFN₅O₂ |
| SMILES: | O=C(NC1=CC(C2=CC3=C(C=C(NC)N=C3)N(CC)C2=O)=C(Br)C=C1F)NC4=CC=CC=C4 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | DCC-2618 is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) KIT and PDGFR-alpha, with IC50 values of 4 nM, 8 nM, 18 nM, 5 nM and 14 nM for WT KIT, V654A KIT, T670I KIT, D816H KIT and D816V KIT, respectively. |
| IC50&Target: | |
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