Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN1720032 Lixisenatide acetate 1997361-87-1
Lixisenatide acetate is aglucagon-like peptide-1 (GLP-1) receptoragonist that can be used in the treatment of type 2 diabetes mellitus (T2DM).
GNF4877 is a potentDYRK1A and GSK3βinhibitor with IC50s of 6 nM and 16 nM, respectively, which leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation (E...
YN310260 SRT 1720 Hydrochloride 2060259-60-9
SRT 1720 Hydrochloride is a selective activator ofSIRT1with an EC50 of 0.10μM, and shows less potent activities on SIRT2 and SIRT3.
YN470039 Calcitriol Derivatives 2070009-24-2
Calcitriol Derivatives is a vitamin D3 analog. v
YN470038 Paricalcitol-D6 2070009-67-3
Paricalcitol-D6 is the deuterated form of Paricalcitol(Zemplar), which is a drug used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure...
MA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4nM, 7.9nM and 10nM for human, mouse and rat PPARδ, respectively. Potential t...
YN480129 HSL-IN-1 2095156-13-9
HSL-IN-1 (compound 24b) is a potent and orally activehormone sensitive lipase (HSL)inhibitor (IC50=2nM) with a significantly reduced reactive metabolite liability.
YN370168 SR-18292 2095432-55-4
SR-18292 inhibits PGC-1α gluconeogenic activity and reduces co-activation of HNF4α by modulating the interaction between GCN5 and PGC-1α.
YN480525 VIT-2763 2095668-10-1
VIT-2763, an oralferroportininhibitor, inhibits hepcidin binding to ferroportin and blocks iron efflux. VIT-2763 has the potential in the treatment of β-thalassemia.
YN480681 DO34 analog 2098969-71-0
DO34 analog is a triazoleDAGL(α)inhibitor extracted from patent WO2017096315 A1, compound 100.
BAY-850 is a potent and isoform selective ATPase family AAA domain-containing protein 2(ATAD2)inhibitor, with an IC50 of 166nM.
YN320228 GPR40 agonist 4 2102196-57-4
GPR40 agonist 4 is a potentfree fatty acid receptor 1(FFA1/ GPR40) agonist with apEC50of 7.54.
YN484289 Ketohexokinase inhibitor 1 2102501-84-6
Ketohexokinase inhibitor 1 is an inhibitor ofketohexokinase (KHK), with IC50s of 8.4nM and 66nM for KHK-C and KHK-A, respectively, extracted from patent US 20170183328 A1, example 4.
AZD3458 is a potent and remarkably selectivePI3Kγinhibitor with pIC50s of 9.1, 5.1, <4.5, and 6.5 forPI3Kγ,PI3Kα,PI3Kβ, and PI3Kδ, respectively.
YN372195 Vildagliptin dihydrate 2133364-01-7
Vildagliptin dihydrate (LAF237 dihydrate) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5nM in human Caco-2 cells. Vildagliptin dihydrate possesses excellent oral bioavailability...
YN370277 KHK-IN-2 2135304-43-5
KHK-IN-2 is a potent and selectiveketohexokinase (KHK)inhibitor with an IC50 of 0.45μM.
YN481176 CE3F4 analog 1 2141967-43-1
CE3F4 analog 1 is an analogue of CE3F4.
YN483626 11-epi-mogroside V 2146088-12-0
11-epi-mogroside V is a mogroside in the fruit ofSiraitia grosvenori. 11-epi-mogroside V exhibits considerable bioactivity in promoting glucose uptake in human HepG2 cells in vitro.
YN373412 Mogroside VI B 2149606-17-5
Mogroside VI B, a cucurbitane glucoside, separated from the crude extract ofSiraitia grosvenorii. Mogroside VI B shows effect on activatingPGC-1αtranscription.
YN481268 Cystathionine-γ-lyase-IN-1 2165706-30-7
Cystathionine-γ-lyase-IN-1 is a selectivecystathionine γ-lyase (CSE)enzyme inhibitor with an IC50 of 6.3μM.
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